GSM1072709[Accession] - GEO DataSets

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Items: 4

Select item 2000439631.

Mtg16 regulates E protein activity and lineage specification in dendritic cell development

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL11154 GPL6246
5 Samples

Download data: BED, CEL

Series

Accession:: GSE43963

ID:: 200043963

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000438762.

Mtg16 regulates E protein activity and lineage specification in dendritic cell development (ChIP-seq)

(Submitter supplied) E protein transcription factors specify major immune cell lineages including lymphocytes and interferon-producing plasmacytoid dendritic cells (pDCs). Corepressors of the ETO family can bind to and block transactivation by E proteins, but the physiological role of these interactions remained unclear. We report that ETO protein Mtg16 binds chromatin primarily through the pDC-specific E protein E2-2 in human pDCs. more...