GSM1081532[Accession] - GEO DataSets - NCBI

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Items: 3

Select item 2000442671.

Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells

(Submitter supplied) Recent studies of genome-wide chromatin interactions have revealed that the human genome is partitioned into many self-associating topological domains. The boundary sequences are enriched for binding sites of CTCF and the cohesin complex, implicating these two factors in the establishment or maintenance of topological domains. To determine the role of cohesin and CTCF in higher order chromatin architecture in human cells, we proteolytically cleaved the cohesin complex from interphase chromatin and examined changes in chromosomal organization as well as transcriptome. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platform:: GPL11154
18 Samples

Download data: BW, RPKM, TXT

Series

Accession:: GSE44267

ID:: 200044267

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000111542.

Illumina HiSeq 2000 (Homo sapiens)

Organism:: Homo sapiens

10422 Series
180547 Samples

Platform

Accession:: GPL11154

ID:: 100011154

Select item 3010815323.

Hi-C, HEK293 siRNA CTCF, replicate one

Organism:: Homo sapiens

Source name:: Hi-C, HEK293 siRNA CTCF

Platform:: GPL11154
Series:: GSE44267

Download data: TXT

Sample

Accession:: GSM1081532

ID:: 301081532

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GSM1081532[Accession] (3)
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