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Items: 4

1.

SUMOylation Regulates the Anti-Proliferative Gene Signature Programs of Glucocorticoid Receptor

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL11154 GPL10558
35 Samples
Download data: BED
Series
Accession:
GSE48379
ID:
200048379
2.

SUMOylation Regulates the Anti-Proliferative Gene Signature Programs of Glucocorticoid Receptor (HEK293)

(Submitter supplied) In addition to the glucocorticoids, the glucocorticoid receptor (GR) is regulated by post-translational modifications, including SUMOylation. We have analyzed how SUMOylation influences the activity of endogenous GR target genes and the receptor chromatin binding by using isogenic HEK293 cells expressing wild-type GR (wtGR) or SUMOylation-defective GR (GR3KR). Gene expression profiling revealed that both dexamethasone up- and down-regulated genes are affected by the GR sumoylation and that the affected genes are significantly associated with pathways of cellular proliferation and survival. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
12 Samples
Download data: TXT
Series
Accession:
GSE48328
ID:
200048328
3.

Illumina HumanHT-12 V4.0 expression beadchip

(Submitter supplied) The HumanHT-12 v4 Expression BeadChip provides high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments. The updated content on the HumanHT-12 v4 Expression BeadChips provides more biologically meaningful results through genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. more...
Organism:
Homo sapiens
51 DataSets
2942 Series
4 Related Platforms
104710 Samples
Download data: TXT
Platform
Accession:
GPL10558
ID:
100010558
4.

GR3KR_vehicle_6h_rep3

Organism:
Homo sapiens
Source name:
Isogenic HEK293 Cells, vehicle treated, 6 h
Platform:
GPL10558
Series:
GSE48328 GSE48379
Download data
Sample
Accession:
GSM1174946
ID:
301174946
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