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Items: 4

1.

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis

(Submitter supplied) The human helicase senataxin (SETX) has been linked to the neurodegenerative diseases amyotrophic lateral sclerosis (ALS4) and ataxia with oculomotor apraxia (AOA2). Here we identified a role for SETX in controlling the antiviral response. Cells that had undergone depletion of SETX and SETX-deficient cells derived from patients with AOA2 had higher expression of antiviral mediators in response to infection than did wild-type cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL10558 GPL16791
58 Samples
Download data: BEDGRAPH
Series
Accession:
GSE52937
ID:
200052937
2.

Analysis of global gene expression profiles of A549 cells treated with SETX siRNA upon Influenza A/PR/8/34(ΔNS1) Infection

(Submitter supplied) Untransfected (no siRNA), control siRNA or SETX siRNA treated A549 cells were infected with A/Puerto Rico/8/1934(ΔNS1) for 4 hours
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL10558
18 Samples
Download data: TXT
Series
Accession:
GSE52932
ID:
200052932
3.

Illumina HumanHT-12 V4.0 expression beadchip

(Submitter supplied) The HumanHT-12 v4 Expression BeadChip provides high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments. The updated content on the HumanHT-12 v4 Expression BeadChips provides more biologically meaningful results through genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. more...
Organism:
Homo sapiens
51 DataSets
2929 Series
4 Related Platforms
104243 Samples
Download data: TXT
Platform
Accession:
GPL10558
ID:
100010558
4.

siSetx treated cells 0h rep 1 (SETX)

Organism:
Homo sapiens
Source name:
A549 cells
Platform:
GPL10558
Series:
GSE52932 GSE52937
Download data
Sample
Accession:
GSM1278309
ID:
301278309
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