GSM1338331[Accession] - GEO DataSets

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Items: 4

Select item 2000555041.

Domains of genomewide gene expression dysregulation in Down syndrome [RNA-seq]

(Submitter supplied) Trisomy 21 (T21) is the most frequent genetic cause of cognitive impairment. To assess the perturbations of gene expression in T21, and to eliminate the noise of the genomic variability, we studied the transcriptome of fetal fibroblasts from a pair of monozygotic twins discordant for T21. Here we show that the differential expression between the twins is organized in domains along all chromosomes that are either up- or downregulated. more...

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL13112 GPL11154 GPL16791
30 Samples

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Accession:: GSE55504

ID:: 200055504

PubMed Similar studies SRA Run Selector

Select item 2000554262.

Domains of genomewide gene expression dysregulation in Down syndrome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Methylation profiling by genome tiling array; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing