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Items: 3

1.

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

(Submitter supplied) SAMHD1 restricts HIV-1 replication in dendritic and other myeloid cells. SAMHD1 has been shown to possess a dGTP-dependent dNTP triphosphatase (dNTPase) activity and is proposed to inhibit HIV-1 replication by depleting the intracellular dNTP pool. Arguing against a role for SAMHD1 dNTPase in HIV-1 restriction, the phosphorylation of SAMHD1 regulates the restriction activity toward HIV-1 without affecting its ability to decrease cellular dNTP levels. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
12 Samples
Download data: TXT
Series
Accession:
GSE58418
ID:
200058418

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
11859 Series
340151 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

3.

U937, WT 3h

Organism:
Homo sapiens
Source name:
U937 monocytic cells infected with HIV-1-GFP
Platform:
GPL16791
Series:
GSE58418
Download data: TXT
Sample
Accession:
GSM1410586
ID:
301410586

SRA Run Selector

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db=gds|term=GSM1410586[Accession]|query=1|qty=2|blobid=MCID_665bf9f6b6fda62199219c5d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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