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Items: 3

1.

Super-Enhancer-mediated Control of Liver Fibrosis by BET Bromodomain Proteins

(Submitter supplied) Here, we investigate the role of enhancers in myofibroblasts, a cell type that dominates the pathogenesis and progression of tissue fibrosis. We reveal that bromodomain and extra-terminal family members (BETs), an important group of epigenetic readers, are critical for super-enhancer-mediated pro-fibrotic gene expression in hepatic stellate cells (HSCs, lipid-containing liver-specific pericytes), upon activation during liver fibrogenesis give rise to myofibroblasts2-4. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL16791
12 Samples
Download data: BEDGRAPH, TXT
Series
Accession:
GSE58680
ID:
200058680

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
11886 Series
340700 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

3.

PolII_S5P-ChIP

Organism:
Homo sapiens
Source name:
human LX2 cells
Platform:
GPL16791
Series:
GSE58680
Download data: BEDGRAPH, TXT
Sample
Accession:
GSM1416815
ID:
301416815

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db=gds|term=GSM1416815[Accession]|query=1|qty=2|blobid=MCID_666f994ece9c6e4cac14e6d6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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