GSM1480323[Accession] - GEO DataSets

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Items: 4

Select item 2000604561.

Analysis of transcription start sites from nascent RNA identifies a unified architecture of initiation at mammalian promoters and enhancers

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL11154 GPL16791
7 Samples

Download data: BIGWIG, BW

Series

Accession:: GSE60456

ID:: 200060456

PubMed Full text in PMC Similar studies

Select item 2000604532.

Analysis of transcription start sites from nascent RNA identifies a unified architecture of initiation at mammalian promoters and enhancers (GRO-cap)

(Submitter supplied) Despite the conventional distinction between promoters and enhancers, they share many features in mammals, including divergent transcription and similar modes of transcription factor (TF) binding. Here, we examine the architecture of transcription initiation genome-wide through comprehensive mapping of transcription start sites (TSSs) in human lymphoblastoid B-cell (GM12878) and chronic myelogenous leukemic (K562) tier 1, ENCODE cell lines using a nuclear run-on protocol called GRO-cap. more...