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Items: 3

1.

Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells

(Submitter supplied) In metazoans, the endoribonuclease SMG6 is thought to cleave many endogenous mRNAs targeted for nonsense-mediated mRNA decay (NMD). However, most evidence as to the identity of endogenous SMG6 substrates is indirect, and little is known about their cleavage sites. Here, we report the efficacy of an RNA degradome approach called parallel analysis of RNA ends (PARE) for identifying NMD intermediates in human cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other
Platform:
GPL16791
36 Samples
Download data: TXT
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

siGL2+siXRN1 Bio1 C-PARE

Organism:
Homo sapiens
Source name:
HeLa+TCRβ68
Platform:
GPL16791
Series:
GSE61398
Download data: TXT
Sample
Accession:
GSM1503895
ID:
301503895
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Supplemental Content

db=gds|term=GSM1503895[Accession]|query=1|qty=2|blobid=MCID_665c6943b6fda6219928962d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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