GSM1515414[Accession] - GEO DataSets

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Items: 4

Select item 2000618251.

Emergence of neural crest identity is a key early step in melanoma formation [ChIP-Seq]

(Submitter supplied) The “cancerized field” concept posits that cells of a given tissue share a potentially oncogenic mutation or insult and are thus cancer-prone, yet only discreet clones within the field initiate tumor formation. In melanoma, tumors frequently (~50%) carry the oncogenic BRAFV600E mutation that is also nearly always present in benign nevi that rarely become melanoma. The zebrafish crestin gene is expressed embryonically in neural crest progenitors and is then specifically re-expressed in melanoma tumors. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL16791
2 Samples

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Accession:: GSE61825

ID:: 200061825

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000753562.

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Danio rerio; Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by array