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Items: 3

1.

Convergent Sense/Antisense Transcription At Intragenic Super-Enhancers Targets AID-initiated Genomic Instability

(Submitter supplied) Activation-induced cytidine deaminase (AID) initiates both somatic hypermutation (SHM) for antibody affinity maturation and DNA breakage for antibody class switch recombination (CSR) via transcription-dependent cytidine deamination of single stranded DNA targets. While largely specific for immunglobulin genes, AID also acts on a limited set of off-targets, generating oncogenic translocations and mutations that contribute to B cell lymphoma. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL17021 GPL16791 GPL13112
9 Samples
Download data: BW
Series
Accession:
GSE62296
ID:
200062296

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2000 (Mus musculus)

Organism:
Mus musculus
8246 Series
187387 Samples
Download data
Platform
Accession:
GPL13112
ID:
100013112

3.

CSR-Act_B_GRO-Seq

Organism:
Mus musculus
Source name:
CSR activated B cells
Platform:
GPL13112
Series:
GSE62296
Download data: BW
Sample
Accession:
GSM1524921
ID:
301524921

SRA Run Selector

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db=gds|term=GSM1524921[Accession]|query=1|qty=3|blobid=MCID_66707f6ece9c6e4cac2b8a3f|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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