GSM1542251[Accession] - GEO DataSets

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Items: 4

Select item 2000631531.

The LSD1/KDM1A neuro-specific isoform regulates neuronal differentiation through H3K9 demethylation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL16791 GPL17586
27 Samples

Download data: BEDGRAPH, CEL, CHP

Series

Accession:: GSE63153

ID:: 200063153

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000582582.

The LSD1/KDM1A neuro-specific isoform regulates neuronal differentiation through H3K9 demethylation [ChIP-Seq]

(Submitter supplied) During brain development, histone-modifying enzymes play an important role by orchestrating transcriptional programs that regulate neuronal maturation. Lysine-Specific Demethylase 1 (LSD1, also named as KDM1A) functions as a transcriptional repressor by removing methyl groups at lysine 4 of histone H3 (H3K4). In neurons, alternative splicing can include an additional exon (exon E8a) within LSD1 transcripts, generating a LSD1+8a neuro-specific isoform. more...