GSM1551879[Accession] - GEO DataSets

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Items: 4

Select item 2000635331.

Transcriptome profiling of HeLa-S3 cells treated with siRNAs targeting LATS1 and/or LATS2

(Submitter supplied) Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular contexts remain poorly understood. Here, we discovered that LATS2 knockout causes dysregulation of PRC2 and subsequent transcriptome changes for differentiation in both mouse and human cells. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10332
4 Samples

Download data: TXT

Series

Accession:: GSE63533

ID:: 200063533

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000635382.

LATS2 regulates repressive epigenetic integrity via regulation of Polycomb repressive complex 2

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; Homo sapiens

Type:: Expression profiling by high throughput sequencing; Expression profiling by array; Non-coding RNA profiling by array; Genome binding/occupancy profiling by high throughput sequencing

6 related Platforms
36 Samples

Download data: BW, TXT

Series

Accession:: GSE63538

ID:: 200063538

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000103323.

Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Feature Number version)

(Submitter supplied) Human 44k Content Refresh Arrays of this design have barcodes that begin with 16026652 or 2526652. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...