GSM1565958[Accession] - GEO DataSets

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Items: 4

Select item 2000641831.

Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing

Platforms:: GPL16791 GPL11154
62 Samples

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Series

Accession:: GSE64183

ID:: 200064183

PubMed Full text in PMC Similar studies

Select item 2000641792.

Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (mRNA-Seq)

(Submitter supplied) DNA methylation is an epigenetic mark thought to be robust to environmental perturbations on a short time scale. Here, we challenge that view by demonstrating that the infection of human dendritic cells with a live pathogenic bacteria is associated with rapid changes in methylation levels at thousands of loci. We performed an integrated analysis of data on genome-wide DNA methylation, histone mark patterns, chromatin accessibility, and gene expression, before and after infection. more...