GSM1566810[Accession] - GEO DataSets

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Items: 4

Select item 2000642371.

The activation of IL-1-induced enhancers depends on TAK1 kinase activity and NF-kappaB p65 II

(Submitter supplied) The inflammatory gene response requires activation of the protein kinase TAK1, but it is currently unknown how TAK1-derived signals coordinate transcriptional programs in the genome. We determined the genome-wide binding of the TAK1-controlled NF-κB subunit p65 in relation to active enhancers and promoters of transcribed genes by ChIP-seq experiments. Out of 35,000 active enhancer regions, 410 H3K4me1-positive enhancers show interleukin (IL)-1-induced H3K27ac and p65 binding. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4133
10 Samples

Download data: TXT

Series

Accession:: GSE64237

ID:: 200064237

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000642242.

The activation of IL-1 induced enhancers depends on TAK1 kinase activity and NF-KB p65

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL16791 GPL4133 GPL6480
44 Samples

Download data: BW, TXT

Series

Accession:: GSE64224

ID:: 200064224

PubMed Full text in PMC Similar studies

Select item 1000041333.

Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...