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Items: 3

1.

Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in Glioblastoma stem-like cells

(Submitter supplied) To identify new therapeutic targets for Glioblastoma (GBM), we performed genome-wide CRISPR-Cas9 "knockout" (KO) screens in patient-derived GBM stem-like cells (GSCs) and human neural stem/progenitors (NSCs), non-neoplastic stem cell controls, for genes required for their in vitro growth. Surprisingly, the vast majority GSC-lethal hits were found outside of molecular networks commonly altered in GBM and GSCs (e.g., oncogenic drivers). more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL16791
16 Samples
Download data: TXT
Series
Accession:
GSE70038
ID:
200070038

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
11886 Series
340700 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

3.

GSC-0827 Day 23 Rep 2

Organism:
Homo sapiens
Source name:
GBM stem-like cells
Platform:
GPL16791
Series:
GSE70038
Download data
Sample
Accession:
GSM1715948
ID:
301715948

SRA Run Selector

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db=gds|term=GSM1715948[Accession]|query=1|qty=2|blobid=MCID_667014a0909a3d46add9f4ad|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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