GSM1722746[Accession] - GEO DataSets

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Items: 4

Select item 2000702771.

Transcriptional repression of IRF7 by MYC is critical for antiviral immune response in human pDC [pDC]

(Submitter supplied) Type I interferons (IFN) are crucial mediators of human innate and adaptive immunity and are massively produced from plasmacytoid dendritic cells (pDC). IRF7 is a critical regulator of type I IFN production when pathogens are detected by TLR7/9 in pDC. However, hyperactivation of pDC can cause life-threatening autoimmune diseases. To avoid the deleterious effects of aberrant pDC activation, tight regulation of IRF7 is required. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
12 Samples

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Series

Accession:: GSE70277

ID:: 200070277

Analyze with GEO2R

Select item 2000702782.

Transcriptional repression of IRF7 by MYC is critical for antiviral immune response in human pDC

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL16791 GPL10558
35 Samples

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Series

Accession:: GSE70278

ID:: 200070278

Analyze with GEO2R

Select item 1000105583.

Illumina HumanHT-12 V4.0 expression beadchip

(Submitter supplied) The HumanHT-12 v4 Expression BeadChip provides high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments. The updated content on the HumanHT-12 v4 Expression BeadChips provides more biologically meaningful results through genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. more...