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Items: 3

1.

Histone H3 globular domain acetylation identifies new class of enhancers

(Submitter supplied) We report the acetylation of lysine residues in the globular domain of H3 (H3K64ac and H3K122ac) marks active gene promoters and also a subset of active enhancers in mouse embryonic stem cells (mESCs), human erythroleukemic cell line (K562). Moreover, we find a novel class of active functional enhancers in ESCs that are marked by H3K122ac but which lack H3K27ac. This work suggests that a more complex analysis of histone acetylation is required to identify enhancers than was previously considered.
Organism:
Mus musculus; Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL13112 GPL16791 GPL17021
10 Samples
Download data: BED, BEDGRAPH
Series
Accession:
GSE66023
ID:
200066023
2.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
3.

K562_Input

Organism:
Homo sapiens
Source name:
K562_Input
Platform:
GPL16791
Series:
GSE66023
Download data
Sample
Accession:
GSM2054698
ID:
302054698
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Supplemental Content

db=gds|term=GSM2054698[Accession]|query=1|qty=3|blobid=MCID_666fa125909a3d46adcf105d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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