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Items: 4

1.

AML1-ETO induces leukemia via C/D box snoRNA/RNPs.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array; Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing
4 related Platforms
94 Samples
Download data: CEL, TXT
Series
Accession:
GSE80602
ID:
200080602
2.

Expression profile of small nucleolar RNA (snoRNA) in acute myeloid leukemia.

(Submitter supplied) Leukemogenesis requires enhanced self-renewal activity, which is induced by specific oncogenes. The underlying molecular mechanisms remain incompletely understood. We transduced mouse lineage negative bone marrow cells (enriched for hematopoietic stem and progenitor cells) with retrovirus expressing leukemic oncogene AML1-ETO9a, MYC and MLL-AF9 as well as empty vector (MIG). We found that all three oncogenes enhanced snoRNA formation. more...
Organism:
Homo sapiens; Mus musculus
Type:
Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL16173 GPL15456
78 Samples
Download data: TXT
Series
Accession:
GSE80523
ID:
200080523
3.

Illumina HiScanSQ (Homo sapiens)

Platform
Accession:
GPL15456
ID:
100015456
4.

Primary diagnosis 120-002

Organism:
Homo sapiens
Source name:
Density centrifuged bone marrow
Platform:
GPL15456
Series:
GSE80523 GSE80602
Download data
Sample
Accession:
GSM2129711
ID:
302129711
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