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Items: 3

1.

Epigenetic profiling of hematopoietic stem cells and leukemia stem cells

(Submitter supplied) The histone 3 lysine 79 (H3K79) methyltransferase Dot1l has been implicated in the development of leukemias bearing translocations that involve the Mixed Lineage Leukemia (MLL) gene. We identified the MLL-fusion targets in a murine MLL-AF9 leukemia model, and conducted epigenetic profiling for H3K79me2, H3K4me3, H3K27me3 and H3K36me3. Histone methylation patterns are highly abnormal on MLL-AF9 fusion target loci, defining a distinct epigenetic lesion involving H3K79. more...
Organism:
Homo sapiens; Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL11002 GPL13112 GPL10999
15 Samples
Download data: WIG
Series
Accession:
GSE29130
ID:
200029130
2.

Illumina Genome Analyzer IIx (Mus musculus)

Platform
Accession:
GPL11002
ID:
100011002
3.

H3K27me3_mLSC_ChIPSeq

Organism:
Mus musculus
Source name:
murine L-GMP
Platform:
GPL11002
Series:
GSE29130
Download data: WIG
Sample
Accession:
GSM721218
ID:
300721218
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db=gds|term=GSM721218[Accession]|query=1|qty=3|blobid=MCID_666f2c46909a3d46adc8b0b0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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