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Items: 3

1.

Widespread regulated alternative splicing of single codons accelerates proteome evolution

(Submitter supplied) Thousands of human genes contain introns ending in NAGNAG motifs (N any nucleotide), where both NAGs can function as 3' splice sites, yielding isoforms differing by inclusion/exclusion of just three bases. However, the functional importance of NAGNAG alternative splicing is highly controversial. Using very deep RNA-Seq data from sixteen human and eight mouse tissues, we found that approximately half of alternatively spliced NAGNAGs undergo tissue-specific regulation and that regulated events have been selectively retained: alternative splicing of strongly tissue-specific NAGNAGs was ten times as likely to be conserved between species as for non-tissue-specific events. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL13112 GPL11002 GPL11154
48 Samples
Download data: GFF, TXT
Series
Accession:
GSE30017
ID:
200030017
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

human_wbc.single

Organism:
Homo sapiens
Source name:
white blood cells
Platform:
GPL11154
Series:
GSE30017
Download data: TXT
Sample
Accession:
GSM742952
ID:
300742952
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Supplemental Content

db=gds|term=GSM742952[Accession]|query=1|qty=3|blobid=MCID_67241791bc40331ebe7b732f|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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