GEO DataSets

(Submitter supplied) We apply a massively parallel reporter assay (MPRA) that relies on mRNA and plasmid tag sequencing (Tag-Seq) to compare the regulatory activities of more than 27,000 distinct variants of two inducible enhancers in human cells: a synthetic cAMP-regulated enhancer and the virus-inducible interferon beta enhancer. The resulting data define accurate maps of functional transcription factor binding sites in both enhancers at single-nucleotide resolution and can be used the to train quantitative sequence-activity models (QSAMs).

Organism:

Escherichia coli; Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL11154 GPL14548

18 Samples

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