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Items: 4

1.

MIWI catalysis is required for piRNA amplification-independent LINE1 transposon silencing [deep sequencing]

(Submitter supplied) Here we show that MIWI is a small RNA-guided ribonuclease (Slicer) that requires extensive complementarity for target cleavage in vitro. Disruption of its catalytic activity in mice by a single point mutation results in male infertility and displays increased accumulation of LINE1 transposon transcripts.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL11002 GPL9250
12 Samples
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Series
Accession:
GSE32184
ID:
200032184
2.

MIWI catalysis is required for piRNA amplification-independent LINE1 transposon silencing

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by array; Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL9250 GPL11002 GPL6246
20 Samples
Download data: CEL
Series
Accession:
GSE32183
ID:
200032183
3.

Illumina Genome Analyzer IIx (Mus musculus)

Platform
Accession:
GPL11002
ID:
100011002
4.

Testes, Adult Miwi -/ADH [MR25]

Organism:
Mus musculus
Source name:
Testes, Adult Miwi -/ADH
Platform:
GPL11002
Series:
GSE32183 GSE32184
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Sample
Accession:
GSM822762
ID:
300822762
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Supplemental Content

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