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Items: 4

1.

Topoisomerase II inhibitors and histone eviction

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
6 related Platforms
62 Samples
Download data: BAM, BED
Series
Accession:
GSE33634
ID:
200033634
2.

Tissue selective effects of topoisomerase II inhibitors in vivo

(Submitter supplied) One major class of anti-cancer drugs targets topoisomerase II to induce DNA double-strand breaks and cell death of fast growing cells. In vitro experiments showed that doxorubicin can induce histone eviction as well as DNA damage, while etoposide can only induce DNA damage. Here, we compare the transcription responses of different tissues to doxorubicin or etoposide treatment in vivo.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6887
30 Samples
Download data: TXT
Series
Accession:
GSE33626
ID:
200033626
3.

Illumina MouseWG-6 v2.0 expression beadchip

(Submitter supplied) The MouseWG-6 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...
Organism:
Mus musculus
31 DataSets
1216 Series
8 Related Platforms
17093 Samples
Download data: BGX, TXT
Platform
Accession:
GPL6887
ID:
100006887
4.

Heart 1 day post doxorubicin rep 1

Organism:
Mus musculus
Source name:
mouse heart
Platform:
GPL6887
Series:
GSE33626 GSE33634
Download data
Sample
Accession:
GSM831676
ID:
300831676
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