GEO DataSets

(Submitter supplied) The salamander has the remarkable ability to regenerate its limb after amputation. Cells at the site of amputation form a blastema and then proliferate and differentiate to regrow the limb. To better understand this process, we have performed deep RNA sequencing of the blastema over a time course. We find genes expressed in three phases with a prominent burst in oncogene expression during the first day, blastemal/limb bud genes peaking at 7 to 14 days, and markers for terminal differentiation upregulated later. more...

Organism:

Ambystoma mexicanum; Mus musculus

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL11002 GPL14997

20 Samples

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