GSM876017[Accession] - GEO DataSets

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Items: 4

Select item 2000402361.

Small RNA and mRNA profiles following TUT knock-down in HeLa

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL11154 GPL9115 GPL10999
7 Samples

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Accession:: GSE40236

ID:: 200040236

PubMed Similar studies

Select item 2000358352.

Small RNA profiles following TUT knock-down in HeLa

(Submitter supplied) The precise control of microRNA (miRNA) biogenesis is important for various cellular functions, and its dysregulation is often associated with human diseases. We previously reported that Terminal uridylyl transferase 4 (TUT4) down-regulates let-7 miRNA biogenesis by oligo-uridylating let-7 precursor (pre-let-7) in mouse embryonic stem cells and that a pluripotency marker Lin28 promotes a processivity of TUT4. more...