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Items: 4

1.

Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
62 Samples
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Series
Accession:
GSE38448
ID:
200038448
2.

Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation (ChIP-Seq)

(Submitter supplied) The expansion of repressive epigenetic marks has been implicated in heterochromatin formation during embryonic development, but the general applicability of this mechanism is unclear. Here we show that nuclear rearrangement of repressive histone marks H3K9me3 and H3K27me3 into non-overlapping structural layers characterizes senescence-associated heterochromatic foci (SAHF) formation in human fibroblasts. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL9115 GPL10999 GPL11154
52 Samples
Download data: BED
Series
Accession:
GSE38442
ID:
200038442
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

Chip Seq H3K9me3 in ER:Ras-induced senescent IMR90 with Lenti-sh-Rb SLX3615

Organism:
Homo sapiens
Source name:
IMR90 Human Diploid Fibroblasts
Platform:
GPL11154
Series:
GSE38442 GSE38448
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Sample
Accession:
GSM942074
ID:
300942074
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