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Items: 3

1.

Identification of direct targets and modified bases of RNA cytosine methyltransferases

(Submitter supplied) We report development of a mechanism-based technique, Aza-IP, that utilizes the stable covalent linkage formed in vivo between an RNA methyltransferase (m5C-RMT) and 5-azacytidine (5-aza-C) incorporated within the target RNA to enable specific target enrichment, coupled with high-throughput sequencing to provide target identification. We apply Aza-IP to two enzyme types, DNMT2 and NSUN2, the latter with important roles in fertility, intellectual ability, stem cells and cancer. more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL11154
7 Samples
Download data: XLS
Series
Accession:
GSE38957
ID:
200038957

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10422 Series
180547 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

DNMT2-Aza-IP

Organism:
Homo sapiens
Source name:
HeLa cells
Platform:
GPL11154
Series:
GSE38957
Download data
Sample
Accession:
GSM952752
ID:
300952752

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db=gds|term=GSM952752[Accession]|query=1|qty=2|blobid=MCID_666569d5ac4a2c1050f81946|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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