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Items: 3

1.

Gene Expression Changes in a Tumor Xenograft by a Py-Im Polyamide

(Submitter supplied) Gene regulation by DNA binding small molecules could have important therapeutic applications. This study reports the investigation of a DNA-binding pyrrole-imidazole polyamide targeted to bind the DNA sequence 5’-WGGWWW-3’ with reference to its potency in a subcutaneous xenograft tumor model. The molecule is capable of trafficking to the tumor site following subcutaneous injection and modulates transcription of select genes in vivo. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL11154 GPL13112
10 Samples
Download data: TXT
Series
Accession:
GSE40218
ID:
200040218
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

vehicle_replicate3_SR

Organism:
Mus musculus
Source name:
vehicle_replicate3_SR
Platform:
GPL13112
Series:
GSE40218
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Sample
Accession:
GSM988522
ID:
300988522
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