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Items: 3

1.

Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells

(Submitter supplied) In this work, we characterized the epigenomic integrity of 17 hiPSC lines derived from six different cell types with varied reprogramming efficiencies. We demonstrate that epigenetic aberrations are a general feature of the hiPSC state and are independent of the somatic cell source. Additionally, we determine that both shared and line-specific epigenetic aberrations in hiPSCs can directly translate into changes in gene expression in both the pluripotent and differentiated states.
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platforms:
GPL10999 GPL11154
65 Samples
Download data: BED
Series
Accession:
GSE40372
ID:
200040372
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

HUES6

Organism:
Homo sapiens
Source name:
HUES6
Platform:
GPL11154
Series:
GSE40372
Download data: BED
Sample
Accession:
GSM992420
ID:
300992420
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