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Items: 3

1.

Integrative Analyses of Gene Expression and DNA Methylation Profiles in a Breast Cancer Cell Line Model of Tamoxifen-Resistance Indicate a Crucial Role of Cells with Stem-like Properties

(Submitter supplied) Purpose: Development of resistance to tamoxifen is an important clinical issue in the treatment of patients with breast cancer. Tamoxifen resistance may be the result of the acquisition of epigenetic regulation such as DNA methylation within breast cancer cells resulting in changed mRNA expression of genes being pivotal for estrogen dependent growth. Alternatively, tamoxifen resistance may be due to selection of preexisting resistant cells, which may exhibit cancer stem-like characteristics or a combination of the two mechanisms. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platform:
GPL11154
10 Samples
Download data: TXT
Series
Accession:
GSE40665
ID:
200040665

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2000 (Homo sapiens)

Organism:
Homo sapiens
10544 Series
183595 Samples
Download data
Platform
Accession:
GPL11154
ID:
100011154

3.

TMAR 7-MMSDK analysis

Organism:
Homo sapiens
Source name:
Breast cancer cell line
Platform:
GPL11154
Series:
GSE40665
Download data
Sample
Accession:
GSM998966
ID:
300998966

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db=gds|term=GSM998966[Accession]|query=1|qty=2|blobid=MCID_67242301bc40331ebe7c3775|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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