Similar studies for GEO DataSets (Select 200043726) - GEO DataSets

Select item 2000437261.

RNA-sequencing (RNA-seq) in breast cancer cell lines after ectopic manipulation of miR-26a expression

(Submitter supplied) RNA sequencing technology has been carried out in order to evaluate mRNA expression changes after manipulation of miR-26a in both MCF-7 and MDA-MB-231 breast cancer cell lines.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
4 Samples

Download data: TXT

Series

Accession:: GSE43726

ID:: 200043726

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001185392.

Differentially expressed genes in human brest cancer specimens

(Submitter supplied) To identify differentially expressed genes in human brest cancer specimens were subjected to Agilent whole genome microarrays.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL20844
4 Samples

Download data: TXT

Series

Accession:: GSE118539

ID:: 200118539

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000628483.

MicroRNA Expression Regulated by the HER2 Isoform HER2D16 in MCF-7 Breast Tumor Cells

(Submitter supplied) The oncogenic isoform of HER2, HER2D16, was stably overexpressed in the MCF-7 breast tumor cell line (MCF-7/HER2D16) and miR expresion profiles between MCF-7 cell lines expressing a vector control (MCF-7/pcDNA) were compared to the MCF-7/HER2D16 cell line.

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL10358
4 Samples

Download data: TXT

Series

Accession:: GSE62848

ID:: 200062848

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000628314.

Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis

(Submitter supplied) Through a series of mouse genetic studies, we concluded that miR-26 overexpression in intestinal epithelial cells inhibits tumor formation in Apcmin/+ mice. We isolated intestinal epithelial cells from M2rtTA and M2rtTA; eGFP.miR-26a to assess gene expression changes after the induction of miR-26a expression.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6887
6 Samples

Download data: TXT

Series

Accession:: GSE62831

ID:: 200062831

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000384155.

Trastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells

(Submitter supplied) Objective: Trastuzumab has been used for the treatment of HER2-positive breast cancer (BC). However, a subset of BC patients exhibited resistance to trastuzumab therapy. Thus, clarifying the molecular mechanism of trastuzumab treatment will be beneficial to improve the treatment of HER2-positive BC patients. In this study, we identified trastuzumab-responsive microRNAs that are involved in the therapeutic effects of trastuzumab. more...

Organism:: Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL10312
8 Samples

Download data: GPR

Series

Accession:: GSE38415

ID:: 200038415

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001510656.

miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling (genomic Variation dataset)

(Submitter supplied) Genomic instability predisposes cells to malignant transformation, however the molecular mechanisms that allow for the propagation of cells with a high-degree of genomic instability remains unclear. Here we report that miR-181a is able to transform fallopian tube secretory epithelial cells- the precursor cell type for the majority of high-grade serous ovarian cancers- through the inhibition of RB1 and simultaneously drives a cell protective inhibition of the stimulator-of-interferon-genes (STING) in order to maintain a microenvironment conducive to the propagation of cells with a high-degree of genomic instability. more...