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Links from GEO DataSets

Items: 12

1.

nELAVL HITS-CLIP and RNA-seq in Alzheimer's Disease patients and IMR-32 neuroblastoma cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL10999 GPL16791 GPL15520
64 Samples
Download data: TXT
Series
Accession:
GSE53699
ID:
200053699
2.

RNAseq in IMR-32 neuroblastoma cells

(Submitter supplied) IMR-32 cells were subjected to lentiviral YRNA infection or nELAVL RNAi and/or UV stress followed by RNAseq analysis to monitor RNA level changes
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
21 Samples
Download data: TXT
3.

RNAseq in Alzheimer's Disease patients

(Submitter supplied) Human brain samples from control and advanced Alzheimer's Diseased patients were subjected to RNAseq analysis to monitor RNA level changes during AD progression
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
17 Samples
Download data: TXT
4.

nELAVL HITS-CLIP in IMR-32 neuroblastoma cells

(Submitter supplied) Non-stressed and UV-stressed IMR-32 cells were subjected to HITS-CLIP to monitor nELAVL binding changes during AD progression
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL15520
9 Samples
Download data: TXT
Series
Accession:
GSE53696
ID:
200053696
5.

nELAVL HITS-CLIP in Alzheimer's Disease patients

(Submitter supplied) Human brain samples from control and advanced Alzheimer's Diseased subjects were subjected to HITS-CLIP to monitor nELAVL binding changes during AD progression
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL10999 GPL15520 GPL16791
17 Samples
Download data: TXT
Series
Accession:
GSE53695
ID:
200053695
6.

Expression data from P0 forebrain of wild-type and Elavl3/Elavl4 double knockout mice.

(Submitter supplied) Neuronal Elavl-like (nElavl) RNA binding proteins have three paralogs (Elavl2, Elavl3 and Elavl4) in the mouse genome. This family of RNABPs have been implicated in a variety of post-transcriptional RNA processing mechanisms, including regulation of mRNA stability, alternative splicing, and translational regulation. In this study, using mouse exon arrays, we identify significant differences (p<0.01) in 119 transcripts between wild-type and Elavl3/Elavl4 double knockout forebrain tissue at postnatal day 0.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6096
10 Samples
Download data: CEL
Series
Accession:
GSE43287
ID:
200043287
7.

Functional Antagonism Between CELF and Mbnl Proteins in Cytoplasm and Nucleus [RNA Bind-N-Seq]

(Submitter supplied) The CUG-BP and ETR-3-like factor 1 (Celf1) RNA binding protein plays an important role in heart and muscle development, and is over-expressed in the disease myotonic dystrophy. Celf1 has known roles in regulation of RNA splicing, RNA stability, and protein translation. To identify transcriptome-wide targets of the Celf1 protein, we performed CLIP-seq against Celf1 using the 3B1 antibody, in myoblasts, heart tissue, and muscle tissue.
Organism:
synthetic construct
Type:
Other
Platform:
GPL15228
7 Samples
Download data: XLSX
Series
Accession:
GSE67337
ID:
200067337
8.

Functional Antagonism Between CELF and Mbnl Proteins in Cytoplasm and Nucleus

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; synthetic construct
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL13112 GPL9250 GPL15228
40 Samples
Download data: BED
Series
Accession:
GSE61893
ID:
200061893
9.

Functional Antagonism Between CELF and Mbnl Proteins in Cytoplasm and Nucleus [CLIP-seq]

(Submitter supplied) The CUG-BP and ETR-3-like factor 1 (Celf1) RNA binding protein plays an important role in heart and muscle development, and is over-expressed in the disease myotonic dystrophy. Celf1 has known roles in regulation of RNA splicing, RNA stability, and protein translation. To identify transcriptome-wide targets of the Celf1 protein, we performed CLIP-seq against Celf1 using the 3B1 antibody, in myoblasts, heart tissue, and muscle tissue.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
3 Samples
Download data: BED, TXT
Series
Accession:
GSE61892
ID:
200061892
10.

Functional Antagonism Between CELF and Mbnl Proteins in Cytoplasm and Nucleus [hearts]

(Submitter supplied) The CUG-BP and ETR-3-like factor 1 (Celf1) RNA binding protein plays an important role in heart and muscle development, and is over-expressed in the disease myotonic dystrophy. Celf1 has known roles in regulation of RNA splicing, RNA stability, and protein translation. To identify transcriptome-wide targets of the Celf1 protein in heart, we performed RNA-Seq of polyA+ RNA from mice inducibly expressing Celf1 in the muscle.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL9250
15 Samples
Download data: TXT
Series
Accession:
GSE61891
ID:
200061891
11.

Functional Antagonism Between CELF and Mbnl Proteins in Cytoplasm and Nucleus [muscle]

(Submitter supplied) The CUG-BP and ETR-3-like factor 1 (Celf1) RNA binding protein plays an important role in heart and muscle development, and is over-expressed in the disease myotonic dystrophy. Celf1 has known roles in regulation of RNA splicing, RNA stability, and protein translation. To identify transcriptome-wide targets of the Celf1 protein in heart, we performed RNA-Seq of polyA+ RNA from mice inducibly expressing Celf1 in the muscle.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL9250
15 Samples
Download data: TXT
Series
Accession:
GSE61890
ID:
200061890
12.

Regulation of the mouse heart transcriptome by Celf1

(Submitter supplied) The CUG-BP and ETR-3-like factor 1 (Celf1) RNA binding protein plays an important role in heart and muscle development, and is over-expressed in the disease myotonic dystrophy. Celf1 has known roles in regulation of RNA splicing, RNA stability, and protein translation. To identify transcriptome-wide targets of the Celf1 protein in heart, we performed RNA-Seq of polyA+ RNA from mice inducibly expressing Celf1 in the heart.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL9250
15 Samples
Download data: TXT
Series
Accession:
GSE56185
ID:
200056185
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