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Links from GEO DataSets

Items: 9

1.
Full record GDS3677

High-fat-diet model: liver

Analysis of liver from obesity-prone (OP) Wistar males with nonalcoholic fatty liver disease (NAFLD) induced by a 16 week, high-fat diet (HFD). Obesity-resistant (OR) males, fed an identical diet, were also examined. Results provide insight into molecular mechanisms underlying NAFLD pathogenesis.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, log ratio, 2 disease state sets
Platform:
GPL4294
Series:
GSE11492
8 Samples
Download data: TXT
DataSet
Accession:
GDS3677
ID:
3677
2.

Transcript Profiling of High Fat Diet induced Obesity-prone and Obesity-resistant Rats

(Submitter supplied) Rodents respond to chronic high fat diet in at least two ways: some of them may readily gain body weight and become obese (termed obesity-prone), and others may not (termed obesity-resistant). An integrated approach of transcript and metabolic profiling of obesity-prone and obesity-resistant rats has been conducted, showing significantly different transcript and metabolic profiles in the two phenotypes. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS3677
Platform:
GPL4294
8 Samples
Download data: TXT
Series
Accession:
GSE11492
ID:
200011492
3.

Gene expression profiles of rat liver tissues after high-fat emulsion feeding

(Submitter supplied) Nonalcoholic fatty liver disease (NAFLD) is a common disorder characterized by excessive hepatic fat accumulation, and potentially resulting in non-alcoholic steatohepatitis (NASH), liver cirrhosis (LC) and end-stage liver disease We used Rat Genome 230 2.0 microarray to further highlight the rat liver tissues after high-fat emulsion feeding.
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL1355
12 Samples
Download data: CEL, CHP, XLS
Series
Accession:
GSE73500
ID:
200073500
4.

Effect of a High Phosphorus Diet on Hepatic Gene Expressions in Rat

(Submitter supplied) A high phosphorus (HP) diet causes disorders of renal function, bone metabolism, and vascular function. We previously demonstrated that DNA microarray analysis is an appropriate method to comprehensively evaluate the effects of a HP diet on kidney dysfunction such as calcification, fibrillization, and inflammation. We reported that type IIb sodium-dependent phosphate transporter is significantly up-regulated in this context. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL1355
8 Samples
Download data: CEL
Series
Accession:
GSE71201
ID:
200071201
5.

Eicosapentaenoic and docosahexaenoic acid-enriched high fat diet delays the development of fatty liver in mice.

(Submitter supplied) To investigate the effects of quality of fat in a high fat diet (HFD) over time on hepatic lipid storage and transcriptome in mice. In this dataset, we include the expression data obtained from dissected mouse liver after being fed with Control, HFD-EPA/DHA and HFD-corn oil diet for 8 and 12 weeks.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL16570
24 Samples
Download data: CEL
Series
Accession:
GSE65370
ID:
200065370
6.

High dietary protein decreases fat deposition induced by high-fat and high-sucrose diet in rats

(Submitter supplied) High-protein diets are known to reduce adiposity in the context of high carbohydrate and Western diets. However, few studies have investigated the specific high-protein effect on lipogenesis induced by a high-sucrose (HS) diet or fat deposition induced by high-fat feeding. We aimed to determine the effects of high protein intake on the development of fat deposition and partitioning in response to high-fat and/or HS feeding. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL6247
6 Samples
Download data: CEL, PDF
Series
Accession:
GSE47570
ID:
200047570
7.

High-fat diet leads to tissue-specific changes reflecting risk factors for diseases in DBA/2J mice

(Submitter supplied) Analysis of tissues of DBA/2 mice fed a standard breeding diet (SBD) and high fat diet (HFD) revealed tissue specific roles in inflammation and disease, and altered communication between tissues. The tissues surveyed incuded adipose tissues (brown, inguinal, mesenteric, retro-peritoneal, subcutaneious and gonadal), muscle and liver.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6105
96 Samples
Download data: TXT
Series
Accession:
GSE15822
ID:
200015822
8.

Orotic acid induced fatty liver disease

(Submitter supplied) A time course of orotic acid induced fatty liver disease. Kyoto and Wistar strain rats were exposed to orotic acid for days 1, 3 and 14. Controls are also included. Keywords = Wistar Keywords = Kyoto Keywords = orotic acid Keywords: time-course
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS765
Platform:
GPL85
14 Samples
Download data
Series
Accession:
GSE665
ID:
200000665
9.
Full record GDS765

Fatty liver disease induced by orotic acid: time course

Expression profiling of livers from inbred Kyotos and outbred Wistars fed a diet with 1% orotic acid to induce fatty liver disease. Profiles examined at various time points up to 14 days. Results used together with NMR spectroscopic analysis of the liver to identify perturbed metabolic pathways.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 2 agent, 2 strain, 4 time sets
Platform:
GPL85
Series:
GSE665
18 Samples
Download data
DataSet
Accession:
GDS765
ID:
765
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