Refine regulatory elements across the genome

G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions. Nat Genet (2023). https://doi.org/10.1038/s41588-023-01437-4

Stromal senescence following treatment with the CDK4/6 inhibitor palbociclib increases mammary cancer metastasis

MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming

Non-conventional β-catenin activity is essential for Notch1-driven T-cell leukemia

CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation

GDF11 rejuvenates neural stem cells via Smad2/3-PI3K-AKT-mTOR and reverses aged-dependent cognitive decline

Effect of Nanoemulsion Targeting on the activation state of neutrophils and monocytes

Polycomb Deficiency Drives a FOXP2-high Aggressive State Targetable by Epigenetic Inhibitors

Total RNA-seq from Patient-Derived Xenograft models of Breast Cancer developed at Baylor College of Medicine

BCL6 is regulated by the RAS/MAPK/ELK axis and promotes KRAS-driven lung cancers

HDAC7 regulates genes essential for the function of FoxP3+ regulatory T cells

Alphavirus infection triggers antiviral RNAi immunity in mammals

EZH2 Catalytic Inhibition Prevents Urothelial Carcinoma Progression Through Immune Activation.

Single-cell multi-omics in human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation.

Single-cell analysis of gene networks in trophoectoderm and inner cell mass during human, monkey and mouse preimplantation development

Multi-omic analysis of cell-of-origin and epigenomic state in pediatric H3K27M gliomas

Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy

Integrated analysis of mRNA and miRNA expression in response to interleukin-6 in hepatocytes

Transcriptional landscape of oncogenic PI3K