Altered Chromatin State Drives Hypersocial Behaviors in Canids

FOXO-regulated Deaf1 controls muscle regeneration through autophagy

The circular RNA circ_ATP8B regulates ROS production and antiviral immunity [circRNA-Seq]

The circular RNA circ_ATP8B regulates ROS production and antiviral immunity

RNAP stalling-derived genome instability underlies ribosomal antibiotics efficacy and resistance evolution (ChIP-seq data)

Integration of ATAC and RNA-Sequencing identifies chromatin and transcriptomic signatures in classical and non-classical zebrafish osteoblasts and indicates mechanisms of entpd5a regulation [ATAC]

A Lactate-induced SREBF2-dependent genetic program drives an immunotolerant dendritic cell population during cancer progression [scATAC-seq]

Single-cell genomics & regulatory networks for 388 human brains

Phase separation of phospho-HDAC6 drives aberrant chromatin architecture in triple-negative breast cancer [ChIP-seq, Cut&Tag, ATAC-seq]

Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth [HiChIP]

Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth

Uncoupling Histone Modification Crosstalk by Engineering Lysine Demethylase LSD1

YTHDC1 m6A-dependent and m6A-independent functions converge to preserve DNA damage response (Ythdc1 ChIP-Seq)

YTHDC1 m6A-dependent and m6A-independent functions converge to preserve DNA damage response

Single cell discovery of m6A RNA modifications in the hippocampus

Genomic context-dependent histone H3K36 methylation by Drosophila methyltransferases

YTHDC1 m6A-dependent and m6A-independent functions converge to preserve DNA damage response (RIP-seq)

Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages [ChIP-seq]

Nuclear receptor Nur77 and Yin-Yang 1 synergistically increase mitochondrial abundance and activity in macrophages.

ZNF143 binds DNA and stimulates transcription initiation to activate and repress direct target genes (ChIP-seq)