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| Status |
Public on Sep 16, 2019 |
| Title |
The C. elegans ortholog of human selenium binding protein 1 is a pro-aging factor protecting against selenite toxicity |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Y37A1B.5, a SELENBP1 ortholog in C. elegans modulates lifespan and stress resistance. Hence transcriptome profiling (RNA-seq) after depletion of Y37A1B.5 via RNAi was performed, aiming to identify targets that would explain these effects.
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| Overall design |
We compared RNAi treatment of Y37A1B.5 for five days to control vector treatment for five days in wildtype worms.
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| Contributor(s) |
Köhnlein K, Groth M, Koch P |
| Citation(s) |
31557719 |
| |
| Submission date |
Jul 12, 2019 |
| Last update date |
Sep 30, 2019 |
| Contact name |
Philipp Koch |
| Organization name |
Leibniz Institute on Aging - Fritz Lipmann Institute
|
| Department |
Core Facility Life Science Computing
|
| Street address |
Beutenbergstraße 11
|
| City |
Jena |
| ZIP/Postal code |
07745 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL18245 |
Illumina HiSeq 2500 (Caenorhabditis elegans) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA554266 |
| SRA |
SRP214438 |
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