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| Status |
Public on Jul 01, 2021 |
| Title |
Expression data from the complex I mutant gas-1 (fc21) C. elegans worms in comparison to wildtype N2 Bristol worm and under the inluence combination drug therapy |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We studied genome-wide expression profiles of C. elegans young adult worms, complex I mutant gas-1(fc21) compare to the wild type N2 Bristol worm and the effect of combination drug treatment on the gene expression profile in gas-1(fc21).
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| Overall design |
4 biological replicates of wildtype (N2 Bristol) synchronized worms grown on OP50 bacteria, 4 biological replicates of the complex I mutant C. elegans synchronized young adults and 4 biological replicates of synchronized complex I mutant worm treated with the different drug combination were used as sources of total RNA. Comparison of the data was intended to reveal causes of different antioxidant drug treatment on gene expresssion profile in the complex I mutant gas-1(fc21) worms.
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| Contributor(s) |
Falk M, Zhang Z, Polyak E, Guha S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Jul 19, 2019 |
| Last update date |
Jul 01, 2021 |
| Contact name |
Zhe Zhang |
| E-mail(s) |
zhezhang@upenn.edu
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| Organization name |
University of Pennsylvania
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| Street address |
Translational Research Lab
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| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
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| Platforms (1) |
| GPL18245 |
Illumina HiSeq 2500 (Caenorhabditis elegans) |
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| Samples (36)
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| Relations |
| BioProject |
PRJNA556493 |
| SRA |
SRP216281 |
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