|
| Status |
Public on Dec 14, 2025 |
| Title |
study on the role and mechanism of SOCS6 in keratinocytes |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Atopic dermatitis is a severe skin disorder. Keratinocytes, as the epidermal barrier cells, are an important component in maintaining the skin barrier function. The role of SOCS6 in keratinocytes is still unclear. In this dataset, we extracted keratinocytes from the foreskin tissue of healthy individuals and conducted mRNA sequencing data for SOCS6 knockdown (KD) and overexpression (OE).
|
| |
|
| Overall design |
Knockdown and overexpression of SOCS6 were respectively compared with the control group to explore the effect of SOCS6 on keratinocytes.
|
| |
|
| Contributor(s) |
Xiao F, Zeng J |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Dec 05, 2025 |
| Last update date |
Dec 15, 2025 |
| Contact name |
Zeng Jinrong |
| E-mail(s) |
zengjinrong1989@csu.edu.cn
|
| Organization name |
the Third Xiangya Hospital, Central South University
|
| Street address |
No.138 Tongzipo Rd, Yuelu District, Changsha, Hunan, China, 410013
|
| City |
Changsha |
| ZIP/Postal code |
410013 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (12)
|
| GSM9352161 |
Human keratinocyte SOCS6 knockdown control 1 |
| GSM9352162 |
Human keratinocyte SOCS6 knockdown control 2 |
| GSM9352163 |
Human keratinocyte SOCS6 knockdown control 3 |
| GSM9352164 |
Human keratinocyte SOCS6 overexpression 1 |
| GSM9352165 |
Human keratinocyte SOCS6 overexpression 2 |
| GSM9352166 |
Human keratinocyte SOCS6 overexpression 3 |
| GSM9352167 |
Human keratinocyte SOCS6 overexpression control 1 |
| GSM9352168 |
Human keratinocyte SOCS6 overexpression control 2 |
| GSM9352169 |
Human keratinocyte SOCS6 overexpression control 3 |
|
| Relations |
| BioProject |
PRJNA1375801 |
Less...
More...