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| Status |
Public on Feb 14, 2018 |
| Title |
Differential gene expression of human melanoma cells [ChIP-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We report the gene expression comparison of human A375 melanoma cells with GDF6 and BMP pathway modulation. These comparisons were used to determine the gene signature regulated by GDF6.
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| Overall design |
Examination of gene expression in one cell type +/- GDF6 knockdown as well as +/- downstream pathway reactivation.
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| |
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| Contributor(s) |
Venkatesan AM, Ceol CJ, Gujja S, Edwards YJ |
| Citation(s) |
29202482 |
| |
| Submission date |
Jun 14, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Dr Yvonne Edwards, PhD |
| Organization name |
University of Massachusetts Medical School
|
| Department |
Program in Molecular Medicine
|
| Lab |
Bioinformatics Core
|
| Street address |
373 Plantation Street
|
| City |
Worcester |
| State/province |
MA |
| ZIP/Postal code |
01605 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE83400 |
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation |
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| Relations |
| BioProject |
PRJNA325676 |
| SRA |
SRP076568 |