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| Status |
Public on Aug 24, 2016 |
| Title |
Ileal expression data of mice fed with diet containing protein from various sources |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
This study was designed to address key questions concerning the use of alternative protein sources for animal feeds and addresses aspects such as their nutrient composition and impact on gut function, the immune system and systemic physiology. We used casein (CAS), partially delactosed whey powder (DWP), spray dried porcine plasma (SDPP), soybean meal (SBM), wheat gluten meal (WGM) and yellow meal worm (YMW) as protein sources.
We investigated the effects of feeding mice during a period of four weeks on semi-synthetic diets containing 30% of six different protein sources. Microarrays were used to detail the global gene expression in the ileal mucosae of mice.
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| Overall design |
Male C57BL/6J mice were stratified according to bodyweight and litter of origin into six dietary treatment groups. These mice were fed for four weeks with semi-synthetic diets containing one of the following protein sources. At the end of four weeks, mice were sacrificed by euthenesia and ileal tissue samples (scrapings) were collected for RNA extraction and hybridization on Affymetrix microarrays. Soybean meal (SBM) diet group served as reference to make comparisons with other experimental diets.
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| Contributor(s) |
Kar SK, Guido H, Schokker D |
| Citation(s) |
28659815 |
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| Submission date |
Jul 15, 2016 |
| Last update date |
Aug 18, 2017 |
| Contact name |
Soumya Kanti Kar |
| E-mail(s) |
soumya.kar@wur.nl
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| Organization name |
WUR
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| Department |
Animal Science Group
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| Lab |
Host Microbe Interactomics
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| Street address |
De Elst1
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| City |
Wageningen |
| State/province |
I am not in the U.S. or Canada |
| ZIP/Postal code |
6708WD |
| Country |
Netherlands |
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| Platforms (1) |
| GPL11533 |
[MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version] |
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| Samples (33)
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| GSM2236237 |
SBM based diet, biological rep3 |
| GSM2236238 |
DWP based diet, biological rep6 |
| GSM2236239 |
CAS based diet, biological rep2 |
| GSM2236240 |
SBM based diet, biological rep4 |
| GSM2236241 |
WGM based diet, biological rep1 |
| GSM2236242 |
CAS based diet, biological rep3 |
| GSM2236243 |
SBM based diet, biological rep5 |
| GSM2236244 |
WGM based diet, biological rep2 |
| GSM2236245 |
CAS based diet, biological rep4 |
| GSM2236246 |
DWP based diet, biological rep1 |
| GSM2236247 |
WGM based diet, biological rep3 |
| GSM2236248 |
CAS based diet, biological rep5 |
| GSM2236249 |
DWP based diet, biological rep2 |
| GSM2236250 |
WGM based diet, biological rep4 |
| GSM2236251 |
SBM based diet, biological rep1 |
| GSM2236252 |
DWP based diet, biological rep3 |
| GSM2236253 |
WGM based diet, biological rep5 |
| GSM2236254 |
DWP based diet, biological rep4 |
| GSM2236255 |
WGM based diet, biological rep6 |
| GSM2236256 |
YMW based diet, biological rep3 |
| GSM2236257 |
SDPP based diet, biological rep1 |
| GSM2236258 |
YMW based diet, biological rep4 |
| GSM2236259 |
SDPP based diet, biological rep2 |
| GSM2236260 |
YMW based diet, biological rep5 |
| GSM2236261 |
SDPP based diet, biological rep3 |
| GSM2236262 |
YMW based diet, biological rep6 |
| GSM2236263 |
SDPP based diet, biological rep4 |
| GSM2236264 |
SDPP based diet, biological rep5 |
| GSM2236265 |
YMW based diet, biological rep1 |
| GSM2236266 |
YMW based diet, biological rep2 |
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| Relations |
| BioProject |
PRJNA329185 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE84442_RAW.tar |
151.5 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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