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Series GSE94687 Query DataSets for GSE94687
Status Public on Aug 22, 2017
Title Next Generation Sequencing Facilitates Quantitative Analysis of FoxO3 or Geminin/FoxO3 depletion on MDA-MB-231 cells Transcriptomes
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We generated 2 Gb of high-quality sequencing data (~1 Gb per sample) and catalogued the expression profiles of 48,162 annotated human genes in each sample. The analysis showed differences of transcriptomes between Control and Geminin/FoxO3 co-depletion expression changes. We identified numerous differentially expressed genes that exhibited distinct expression patterns. These genes are appealing candidates for further investigation of the gene expression and associated regulatory mechanisms by Geminin and FoxO3 .
 
Overall design MDA-MB-231 mRNA profiles of Control, FoxO3 and Geminin/FoxO3 co-depletion were generated by deep sequencing, using Illumina HiSeq4000.
 
Contributor(s) You H, Zhang L
Citation(s) 28436938
Submission date Feb 08, 2017
Last update date May 15, 2019
Contact name Lei Zhang
E-mail(s) zhanglei@xmu.edu.cn
Phone +86-15960285971
Organization name Xiamen University
Department School of Life Sciences
Lab State Key Laboratory of Cellular Stress Biology
Street address Xiang'an Nan Road
City Xiamen
State/province Fujian
ZIP/Postal code 361000
Country China
 
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (3)
GSM2480876 Co
GSM2480877 sF_3
GSM2480878 sG_sF_3
Relations
BioProject PRJNA371816
SRA SRP099073

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE94687_RAW.tar 940.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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