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Status |
Public on Aug 22, 2017 |
Title |
Next Generation Sequencing Facilitates Quantitative Analysis of FoxO3 or Geminin/FoxO3 depletion on MDA-MB-231 cells Transcriptomes |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
We generated 2 Gb of high-quality sequencing data (~1 Gb per sample) and catalogued the expression profiles of 48,162 annotated human genes in each sample. The analysis showed differences of transcriptomes between Control and Geminin/FoxO3 co-depletion expression changes. We identified numerous differentially expressed genes that exhibited distinct expression patterns. These genes are appealing candidates for further investigation of the gene expression and associated regulatory mechanisms by Geminin and FoxO3 .
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Overall design |
MDA-MB-231 mRNA profiles of Control, FoxO3 and Geminin/FoxO3 co-depletion were generated by deep sequencing, using Illumina HiSeq4000.
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Contributor(s) |
You H, Zhang L |
Citation(s) |
28436938 |
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Submission date |
Feb 08, 2017 |
Last update date |
May 15, 2019 |
Contact name |
Lei Zhang |
E-mail(s) |
zhanglei@xmu.edu.cn
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Phone |
+86-15960285971
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Organization name |
Xiamen University
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Department |
School of Life Sciences
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Lab |
State Key Laboratory of Cellular Stress Biology
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Street address |
Xiang'an Nan Road
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City |
Xiamen |
State/province |
Fujian |
ZIP/Postal code |
361000 |
Country |
China |
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Platforms (1) |
GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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Samples (3) |
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Relations |
BioProject |
PRJNA371816 |
SRA |
SRP099073 |