|
| Status |
Public on Apr 01, 2020 |
| Title |
Effect of INO80 loss on open chromatin in HepG2 cells [ATAC-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Other
|
| Summary |
Loss of INO80 from INO80 canonical bound regions decreases open chromatin. Loss of INO80 did not affect chromatin accessibility at autonomous sites.
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| |
|
| Overall design |
Two indepdent siRNAs targeting INO80 were used to deplete HepG2 cells followed by ATAC-seq library preparation as described in Buenrostro et al. 2013). Data were generated from three independent siRNA transductions.
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| |
|
| Contributor(s) |
Raab JR, Magnuson T |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Apr 05, 2017 |
| Last update date |
Apr 02, 2020 |
| Contact name |
Jesse Raab |
| E-mail(s) |
jraab@med.unc.edu
|
| Organization name |
University of North Carolina Chapel Hill
|
| Department |
Genetics
|
| Street address |
120 Mason Farm Rd
|
| City |
Chapel Hill |
| ZIP/Postal code |
27599 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (9)
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| This SubSeries is part of SuperSeries: |
| GSE97413 |
INO80 complex assembly is antagonized by PRC2. |
|
| Relations |
| BioProject |
PRJNA381707 |
| SRA |
SRP103081 |
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