Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Select item 19631221.

NanoBRET assay (JAK2, SGC Frankfurt)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:2 Tested

AID:: 1963122

Summary Related BioAssays by Target

Select item 19591652.

Inhibition of JAK2 (unknown origin) at 1000 nM by by DiscoverX KINOMEscan assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Active, 1 Tested

AID:: 1959165

Summary Related BioAssays by Target

Select item 19591613.

Inhibition of JAK2 (unknown origin) at 1000 nM by by DiscoverX KINOMEscan assay relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Tested

AID:: 1959161

Summary Related BioAssays by Target

Select item 19587864.

Inhibition of JAK2 (unknown origin)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:10 Activity ≤ 1 µM, 10 Tested

AID:: 1958786

Summary Related BioAssays by Target

Select item 19559115.

Inhibition of JAK2 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Tested

AID:: 1955911

Summary Related BioAssays by Target

Select item 19519246.

Inhibition of JAK2 dependent GM-CSF stimulated STAT3 phosphorylation in human TF-1 cells

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Active, 1 Tested

AID:: 1951924

Summary Related BioAssays by Target

Select item 19498067.

Inhibition of JAK2 (unknown origin)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1949806

Summary Related BioAssays by Target

Select item 19494258.

Inhibition of JAK (unknown origin)

Source:: ChEMBL

Protein Targets:: Non-receptor tyrosine-protein kinase TYK2; ...
Total:: 4

Assay data:5 Active, 5 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested

AID:: 1949425

Summary Related BioAssays by Target

Select item 19490419.

Inhibition of JAK2 (unknown origin) by Ambit kinase assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:4 Tested

AID:: 1949041

Summary Related BioAssays by Target

Select item 194880910.

Inhibition of GST-fused JAK2 (808 to 1132 residues) (unknown origin) using Carboxyfluorescein-Ahx-GGEEEEYFELVKKKK peptide as substrate incubated for 60 mins in presence of ATP by Janus kinase assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:5 Active, 4 Activity ≤ 1 µM, 5 Tested

AID:: 1948809

Summary Related BioAssays by Target

Select item 194837011.

Inhibition of JAK2 (unknown origin)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Tested

AID:: 1948370

Summary Related BioAssays by Target

Select item 194247812.

Inhibition of JAK2 (unknown origin)

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1942478

Summary Related BioAssays by Target

Select item 194198913.

Inhibition of JAK2 (unknown origin) assessed as inhibition constant

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1941989

Summary Related BioAssays by Target

Select item 194198714.

Inhibition of full length JAK2 V617F mutant (unknown origin) by JAK radiometric filter binding kinase assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1941987

Summary Related BioAssays by Target

Select item 194198615.

Inhibition of full length wild type JAK2 (unknown origin) by JAK radiometric filter binding kinase assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1941986

Summary Related BioAssays by Target

Select item 194198316.

Competitive inhibition of JAK2 (unknown origin) in the presence of ATP by JAK radiometric filter binding kinase assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1941983

Summary Related BioAssays by Target

Select item 194197417.

Inhibition of human JAK2 kinase domain incubated for 1 hrs in the presence of ATP by spectrophotometric analysis

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1941974

Summary Related BioAssays by Target

Select item 194197018.

Inhibition of IL-3 stimulated wild type JAK2-mediated signalling in mouse BaF3 cells preincubated with compound for 5 hrs followed by IL-3 stimulation and measured after 20 mins by Alphascreen SureFire assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Active, 1 Tested

AID:: 1941970

Summary Related BioAssays by Target

Select item 194196619.

Inhibition of JAK2 (unknown origin) by Lanthascreen kinase assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1941966

Summary Related BioAssays by Target

Select item 194195820.

Inhibition of wild-type JAK2 (unknown origin) expressed in baculovirus expression system using (biotinyl-amino-hexanoyl)EQEDEPEGDYFEWLE-amide as substrate preincubated with substrate for 60 mins followed by compound addition and measured after 20 mins by time-resolve fluorescence assay

Source:: ChEMBL

Protein Target:: Tyrosine-protein kinase JAK2

Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1941958

Summary Related BioAssays by Target

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Proteins (9)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (847)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (184)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (691)
BioAssays with the active concentration of tested reagents less than 1 micromolar

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BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (914)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (3)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose

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BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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Literature Extraction (1,462)
BioAssays extracted from the literature
NIH MLP (7)
BioAssays deposited by the NIH Molecular Libraries Program
Other (50)
BioAssays deposited by other experimentalists

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