An Interactive Database for the Assessment of Histone Antibody Specificity

Mol Cell. 2015 Aug 6;59(3):502-11. doi: 10.1016/j.molcel.2015.06.022. Epub 2015 Jul 23.

Abstract

Access to high-quality antibodies is a necessity for the study of histones and their posttranslational modifications (PTMs). Here we debut the Histone Antibody Specificity Database (http://www.histoneantibodies.com), an online and expanding resource cataloging the behavior of widely used, commercially available histone antibodies by peptide microarray. This interactive web portal provides a critical resource to the biological research community that routinely uses these antibodies as detection reagents for a wide range of applications.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Antibodies / metabolism*
  • Antibody Specificity
  • Databases, Genetic*
  • HeLa Cells
  • Histones / metabolism*
  • Humans
  • Protein Array Analysis / methods*
  • Protein Processing, Post-Translational

Substances

  • Antibodies
  • Histones