DataSet Record GDS1405: Expression Profiles Data Analysis Tools Sample Subsets
Title: Pulmonary type II cell differentiation
Cluster AnalysisGDS1405 Cluster Image
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Summary: Analysis of epithelial cells isolated from 13 fetal lungs (13-20 wks old) and cultured in dexamethasone/cyclic AMP/isobutylmethylxanthine (DCI) for 72 hrs to promote type II cell differentiation. Mature alveolar type II cells that produce surfactant are critical for adaptation to extrauterine life.
Organism: Homo sapiens
Platform: GPL96: [HG-U133A] Affymetrix Human Genome U133A Array
Citations:
  • Wade KC, Guttentag SH, Gonzales LW, Maschhoff KL et al. Gene induction during differentiation of human pulmonary type II cells in vitro. Am J Respir Cell Mol Biol 2006 Jun;34(6):727-37. PMID: 16474099
  • McDevitt TM, Gonzales LW, Savani RC, Ballard PL. Role of endogenous TGF-beta in glucocorticoid-induced lung type II cell differentiation. Am J Physiol Lung Cell Mol Physiol 2007 Jan;292(1):L249-57. PMID: 16997883
Reference Series: GSE3306 Sample count: 10
Value type: count Series published: 2005/09/21