DataSet Record GDS2486: Expression Profiles Data Analysis Tools Sample Subsets
Title: Small airway epithelium response to cigarette smoking
Cluster AnalysisGDS2486 Cluster Image
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Summary: Analysis of small airway epithelial cells of phenotypically normal smokers. The earliest morphologic evidence of changes in the airways associated with chronic cigarette smoking is in the small airways. Results provide insight into how smoking modifies small airway structure and function.
Organism: Homo sapiens
Platform: GPL570: [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citations:
  • Harvey BG, Heguy A, Leopold PL, Carolan BJ et al. Modification of gene expression of the small airway epithelium in response to cigarette smoking. J Mol Med (Berl) 2007 Jan;85(1):39-53. PMID: 17115125
  • Tilley AE, Harvey BG, Heguy A, Hackett NR et al. Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2009 Mar 15;179(6):457-66. PMID: 19106307
Reference Series: GSE4498 Sample count: 22
Value type: count Series published: 2006/11/21