DataSet Record GDS2658: Expression Profiles Data Analysis Tools Sample Subsets
Title: Histone deacetylase Sirt1 overexpression effect on the heart
Cluster AnalysisGDS2658 Cluster Image
Download
Summary: Analysis of transgenic hearts overexpressing Sirt1, a class III histone deacetylase. Sirt1 protects against apoptosis and mediates the survival of cardiac myocytes and neurons under stress in vitro. Results provide insight into the in vivo function of Sirt1 in the heart.
Organism: Mus musculus
Platform: GPL1261: [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
Citation:
  • Alcendor RR, Gao S, Zhai P, Zablocki D et al. Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 2007 May 25;100(10):1512-21. PMID: 17446436
Reference Series: GSE7407 Sample count: 4
Value type: transformed count Series published: 2007/03/31