Inflammatory breast cancer cell line response to TIG1 depletion
Summary:
Analysis of SUM149 inflammatory breast cancer (IBC) cells depleted for TIG1. TIG1 depletion decreased IBC cell proliferation, migration, and invasion in vitro and inhibited tumor growth of IBC cells in vivo. Results provide insight into the role of TIG1 in the pathogenesis and progression of IBC.
GPL570:
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Citation:
Wang X, Saso H, Iwamoto T, Xia W et al. TIG1 promotes the development and progression of inflammatory breast cancer through activation of Axl kinase. Cancer Res 2013 Nov 1;73(21):6516-25. PMID: 24014597
