Forkhead box O 1,3,4 muscle-specific knockout effect on fasted gastrocnemius muscle
Summary:
Analysis of gastrocnemius muscle from starved males with muscle-specific deletion of Forkhead Box O transcription factors 1, 3 and 4 (FoxO1,3,4-/-). Results provide insight into the collective roles of FoxOs during muscle atrophy.
Milan G, Romanello V, Pescatore F, Armani A et al. Regulation of autophagy and the ubiquitin-proteasome system by the FoxO transcriptional network during muscle atrophy. Nat Commun 2015 Apr 10;6:6670. PMID: 25858807